Time-restricted Eating for the Prevention and Management of Metabolic Diseases | Dr. Varsha Jagtap | Endocrinologist in Pune

Dr. Varsha Jagtap | Best Endocrinologist in Pune


Time-restricted eating and time-restricted feeding are behavioral intervention approaches that are focused on the physiological effects of varying biological rhythms on metabolism and caloric intake. 
The concept of circadian rhythms has been used to describe the rhythm of the night. It is believed that the central nervous system's sleep-wake cycle is influenced by the rhythm of the night.
The findings of the current study revealed that maintaining a consistent daily dose of nutrition can sustain robust circadian rhythms. This study supports the notion that adopting a healthy lifestyle can improve the quality of life for people with circadian rhythms.
Results of pilot human intervention studies have shown that consistent fasts with a long overnight fast can help lower the risk of various chronic diseases. However, more studies are needed to analyze the effects of TRE alone or as an adjuvant lifestyle intervention.

ESSENTIAL POINTS

• Time-restricted eating or feeding (TRE or TRF) is a nutrition intervention approach in which daily caloric intake is restricted to a consistent window of approximately 8 to 10 hours.
• In preclinical animal models, TRF without reducing caloric intake has been shown to prevent or attenuate severity of several metabolic diseases, including obesity, glucose intolerance, hepatic steatosis, dyslipidemia, and age-related decline in cardiac function.
• In pilot human studies, TRE with or without explicit calorie reduction can reduce body weight, glucose intolerance, hypertension, and dyslipidemia.
• TRF is based on the concepts of circadian rhythm and in animal models is shown to improve metabolism by at least partly acting through the molecular circadian clock.Molecular studies in preclinical animal models show TRF exerts pleiotropic effects on multiple pathways in different organs and on gut microbiome composition.
• Better methods to monitor and promote compliance to a daily eating pattern in humans is necessary to accurately assess TRE benefits.